In recent years, skin rejuvenation has evolved beyond the traditional focus on volume restoration or surface-level correction. Instead, modern treatment approaches are placing greater emphasis on skin quality, overall facial harmony, and safety in clinical practice. This shift is also why solutions that support collagen stimulation and dermal restructuring from within are receiving increasing attention from aesthetic professionals.
This treatment philosophy was clearly reflected in the scientific workshop titled “The Application of PDLLA-CMC in Skin Rejuvenation: From Collagen-Stimulating Efficacy to Clinical Safety,” co-organized by the University Medical Center Ho Chi Minh City and Grassroots on March 15, 2026. The program offered a multidimensional perspective on AestheFill PDLLA-CMC, covering its mechanism of action, clinical response, and important safety considerations in real-world treatment settings.
AestheFill PDLLA-CMC and Today’s Rejuvenation Trends
As aesthetic expectations continue to change, treatment goals are changing as well. While immediate visible results were once the primary focus, skin rejuvenation today is increasingly moving toward outcomes that look more natural, feel softer, and place greater value on tissue quality.
Within this context, AestheFill PDLLA-CMC is being discussed as part of a regenerative approach to skin rejuvenation, rather than simply as a product associated with superficial change. This reflects a direction that is becoming more relevant in modern aesthetic dermatology, where long-term skin quality and structural support are gaining greater clinical importance.
A Scientific Workshop Featuring Leading Experts in Aesthetic Dermatology
The workshop was chaired by Assoc. Prof. Dr. Le Thai Van Thanh, Head of the Department of Dermatology and Skin Aesthetics at the University Medical Center Ho Chi Minh City, and Senior Lecturer in Dermatology at the University of Medicine and Pharmacy at Ho Chi Minh City.
The speaker panel included Dr. Camelo Crisafulli (Italy), MSc. Dr. Pham Cam Thuy, MSc. Dr. Ta Quoc Hung, and Specialist Level II Dr. Thach Van Toan. The participation of both Vietnamese and international experts brought academic depth to the program while also making the discussions highly relevant to daily clinical practice in Vietnam.
AestheFill PDLLA-CMC in Regenerative Skin Rejuvenation
At the workshop, Dr. Camelo Crisafulli shared insights into the use of PDLLA-CMC in improving visible signs of aging. His presentation highlighted a regenerative approach to skin rejuvenation, where treatment goals are no longer limited to immediate visual correction, but instead aim for natural-looking enhancement, facial harmony, and progressive improvement over time.
In this context, AestheFill was presented as a solution associated with collagen stimulation and dermal restructuring, aligning with the direction of modern rejuvenation strategies. Its presence in scientific discussions also reflects the growing clinical interest in approaches that go beyond surface correction and instead focus on improving tissue quality from within.
Clinical Response and Safety in PDLLA-CMC Applications
From a practical perspective, the workshop extended beyond mechanism of action to address clinical response and safety in actual use.
MSc. Dr. Pham Cam Thuy presented an evaluation of clinical response following PDLLA-CMC treatment in Vietnam. Her presentation contributed valuable real-world insight, helping attendees better understand the clinical relevance and potential role of this approach in the local setting.
In addition, MSc. Dr. Ta Quoc Hung shared safety strategies and complication management approaches related to the use of PDLLA-CMC. This part of the program reinforced an important principle in aesthetic medicine: efficacy cannot be separated from safety. In clinical practice, outcomes depend not only on the product itself, but also on physician experience, careful patient selection, and an appropriate treatment strategy for each individual case.
Live Demonstration Bridging Theory and Practice
Alongside the academic presentations, the workshop also featured a live demonstration of PDLLA-CMC applications for rejuvenation of the face, neck, and hands, performed by Specialist Level II Dr. Thach Van Toan. This session helped attendees better visualize how the approach can be applied in real treatment settings, while also strengthening the connection between scientific knowledge and hands-on clinical practice.
What Is AestheFill?
AestheFill is a product composed of microparticles containing PDLLA (Poly-D,L-Lactic Acid) combined with CMC (Carboxymethylcellulose). It supports the body’s natural collagen stimulation process, contributing to dermal regeneration from within and promoting longer-term rejuvenation outcomes.
The introduction of AestheFill PDLLA-CMC within the framework of this scientific workshop also shows that the product is being positioned within a broader trend in skin rejuvenation—one that increasingly values mechanism-driven treatment, appropriate clinical indication, and closer patient monitoring.
AestheFill – A Natural, Science-Driven, and Sustainable Rejuvenation Solution
Explore more about LDLLA-CMC technology and the science of collagen-based rejuvenation
