Teoxane’s signature technology is RHA® – Resilient Hyaluronic Acid, developed to better adapt to the natural movement of the face. According to Teoxane, this platform allows fillers to maintain flexibility, elasticity, and structural integrity in highly mobile areas such as those involved in speaking, smiling, and facial expression. The product portfolio is clearly segmented according to treatment goals:
- TEOSYAL RHA® 1–4: dynamic fillers for wrinkles and expressive areas
- TEOSYAL® Ultra Deep: structural support and deep volume restoration
- Redensity 1: a skin booster designed to hydrate, restructure, and improve overall skin quality
- Redensity 2: a dedicated solution for the delicate and thin periocular area
TEOSYAL® PURESENSE REDENSITY 1 is specifically designed to improve overall skin quality. Through its hydrating and regenerative properties, it helps protect the skin and combat oxidative stress. All treatment protocols incorporating TEOSYAL® PURESENSE REDENSITY 1 contribute to skin protection and rejuvenation.
Product Role
TEOSYAL® PURESENSE REDENSITY 1 enhances dermal restructuring, enabling the skin to restore density and stimulate cellular regeneration. It is recognized as an advanced innovation in aesthetic enhancement, delivering natural, visible, and scientifically proven results. The synergistic action of high molecular weight Hyaluronic Acid and a dermo-restructuring complex has been scientifically demonstrated to improve skin quality:
- +98% Collagen IV: Reinforces the dermo-epidermal junction (DEJ) and promotes tissue restructuring
- +1400% GAGs*: Enhances deep hydration
- +26% Fibrillin-1: Improves skin firmness and supports tissue remodeling
- −28% MDA: Provides antioxidant protection
Recommended Treatment Protocol
- Initial phase: 3 sessions – 1 session per month
- Maintenance phase: 3 sessions per year
Composition
- Hyaluronic Acid (HA) concentration: 15 mg/mL
- Non-crosslinked Hyaluronic Acid
- A complex of 14 essential nutrients, including: 8 amino acids, 3 antioxidants, 2 minerals, 1 vitamin
- Lidocaine 0.3%
Indications & Injection Protocol
- Indications: Skin brightening, hydration enhancement, and prevention of signs of aging on the face, neck, and décolleté
- Injection depth: Mid- to superficial dermis
- Injection technique: Micro-bolus
TEOSYAL® PURESENSE REDENSITY 2 is the only dermal filler specifically designed for the delicate and challenging periorbital area. This highly sensitive zone requires a dedicated formulation to ensure both safety and efficacy.
TEOSYAL® PURESENSE REDENSITY 2 delivers immediate, natural-looking results with a high safety profile. When combined with R[II] Eyes, a complementary at-home skincare solution, it helps optimize brightening and rejuvenation outcomes for the eye contour.
Product Role
TEOSYAL® PURESENSE REDENSITY 2 is uniquely indicated for the periorbital area. It effectively treats tear trough deformities by restoring volume and correcting hollow under-eye areas. In addition, it rejuvenates the eye contour, improves pigmentation-related dark circles, and enhances overall skin tone, resulting in a fresher, more radiant, and revitalized appearance.
Duration of Effect
Approximately 9–12 months
Composition
- Hyaluronic Acid (HA) concentration: 15 mg/mL
- A combination of non-crosslinked and crosslinked Hyaluronic Acid
- A dermo-restructuring complex of 14 essential nutrients, including: 8 amino acids, 3 antioxidants, 2 minerals, 1 vitamin
- Lidocaine 0.3%
Indications & Injection Protocol
- Indications: Dedicated treatment for the eye contour, including correction of under-eye imperfections and tear trough deformities
- Injection depth: Supraperiosteal plane (deep fat compartment / infraorbital area)
- Injection technique: Small-volume injections (maximum 0.5 mL), using bolus or linear threading techniques
TEOSYAL® RHA 1 is part of the RHA (Resilient Hyaluronic Acid) range by Teoxane. Featuring the exclusive RHA technology, TEOSYAL® RHA 1 is specifically designed to support skin regeneration, smooth fine and superficial wrinkles on the face and neck, while preserving natural facial dynamics.
Product Role
- Smooths fine and superficial lines
- Restores skin softness and elasticity
- Enhances overall skin quality, promoting a more even and healthy-looking complexion
Duration of Effect
Approximately 9–12 months
Composition
- Hyaluronic Acid (HA) concentration: 15 mg/mL
- A combination of crosslinked Hyaluronic Acid and native HA, optimized for enhanced softness and flexibility
- Lidocaine 0.3%: improves patient comfort during injection
Indications & Injection Protocol
- Indications: Treatment of dynamic areas presenting fine and superficial wrinkles, including perioral lines, crow’s feet, neck lines, and wrinkles in the décolleté area
- Injection depth: Mid-dermis
- Injection technique: Linear threading and cross-hatching techniques, particularly suitable for barcode lines (upper lip area)
TEOSYAL® RHA 2 is a premium dermal filler developed in Switzerland, designed to treat dynamic wrinkles in the upper face, including the forehead, crow’s feet, and perioral lines. Powered by advanced RHA technology, TEOSYAL® RHA 2 effectively fills moderate wrinkles in highly mobile areas, restores skin elasticity, and delivers a naturally smooth and refreshed appearance.
Product Role
TEOSYAL® RHA 2 is indicated for lip volumization and the correction of moderate wrinkles in the upper face and perioral area. In aging skin, it provides subtle volume restoration while preserving natural facial expressions and dynamic movement.
Duration of Effect
Approximately 9–18 months
Composition
- Hyaluronic Acid (HA) concentration: 23 mg/mL
- Crosslinked Hyaluronic Acid with high elasticity and resilience
- Lidocaine 0.3%: enhances patient comfort during injection
Indications & Injection Protocol
- Indications: Treatment of forehead lines and lip enhancement
- Injection depth: Mid-dermis or lip mucosa
- Injection technique: Bolus or linear threading techniques
TEOSYAL® RHA 3 is part of the RHA (Resilient Hyaluronic Acid) range by Teoxane, specifically designed to treat deep folds in highly dynamic areas, enhance facial contours, and deliver natural-looking results. It is an ideal choice for patients seeking visible rejuvenation while maintaining facial expressiveness.
Product Role
Formulated with advanced crosslinked Hyaluronic Acid, TEOSYAL® RHA 3 effectively fills pronounced wrinkles and folds such as nasolabial folds and perioral lines. It also restores volume in areas such as the upper cheeks and provides subtle cheek enhancement for a naturally lifted appearance. Additionally, TEOSYAL® RHA 3 can be used for lip enhancement, creating soft, naturally plumped lips.
Duration of Effect
Approximately 12–20 months
Composition
- Hyaluronic Acid (HA) concentration: 23 mg/mL
- Crosslinked Hyaluronic Acid
- Lidocaine 0.3%: enhances patient comfort during injection
Indications & Injection Protocol
- Indications: Treatment of deep wrinkles in dynamic areas and lip enhancement (e.g., nasolabial folds, marionette lines)
- Injection depth: Deep dermis or superficial fat compartments
- Injection technique: Bolus or linear threading techniques
TEOSYAL® RHA 4 is a premium dermal filler from the RHA (Resilient Hyaluronic Acid) range by Teoxane, specifically developed for the treatment of advanced signs of facial aging.
TEOSYAL® RHA 4 restores lost volume, restructures facial contours, and delivers firmer, smoother, and more youthful-looking skin. It is an ideal solution for patients presenting with deep wrinkles and significant volume loss, particularly in cases of advanced dermal aging.
Product Role
TEOSYAL® RHA 4 is indicated for significant volume restoration in areas such as hollow cheeks, sunken temples, and central facial sagging due to aging. It helps re-establish facial balance and harmony while preserving natural facial expressions
Duration of Effect
Approximately 12–22 months
Composition
- Hyaluronic Acid (HA) concentration: 23 mg/mL
- Crosslinked Hyaluronic Acid
- Lidocaine 0.3%: enhances patient comfort during injection
Indications & Injection Protocol
- Indications: Cheeks, cheekbones, temples, and facial contouring
- Injection depth: Subcutaneous layer (superficial fat compartment beneath the dermis)
- Injection technique: Bolus or fanning techniques
TEOSYAL® Ultra Deep is a structural dermal filler designed to provide deep tissue support and lifting capacity within the deep fat compartments. It has been specifically developed by Teoxane to deliver optimal structural projection and support.
Product Role
TEOSYAL® Ultra Deep enables a natural lifting effect and well-defined contouring without the need for surgical intervention. It is particularly suitable for enhancing facial harmony and balance in areas such as the chin and jawline, providing strong projection and structural definition.
Duration of Effect
Approximately 9–20 months
Composition
- Hyaluronic Acid (HA) concentration: 25 mg/mL
- Crosslinked Hyaluronic Acid
- Lidocaine 0.3%: enhances patient comfort during injection
Indications & Injection Protocol
- Indications: Chin and cheek augmentation
- Injection depth: Subcutaneous layer (deep fat compartments, close to the periosteum)
- Injection technique: Supraperiosteal injections
Teoxane’s signature technology is RHA® – Resilient Hyaluronic Acid, developed to better adapt to the natural movement of the face. According to Teoxane, this platform allows fillers to maintain flexibility, elasticity, and structural integrity in highly mobile areas such as those involved in speaking, smiling, and facial expression.
The product portfolio is clearly segmented according to treatment goals:
- TEOSYAL RHA® 1–4: dynamic fillers for wrinkles and expressive areas
- TEOSYAL® Ultra Deep: structural support and deep volume restoration
- Redensity 1: a skin booster designed to hydrate, restructure, and improve overall skin quality
- Redensity 2: a dedicated solution for the delicate and thin periocular area
Teoxane approaches treatment according to anatomical area, tissue depth, and degree of aging, rather than relying on a single material for every indication. RHA® is designed for areas where natural facial expression should be preserved; Ultra Deep is intended for lift and deep structural support; Redensity 1 focuses on skin quality; and Redensity 2 is specifically suited for the tear trough and periocular region.
All Teoxane injectable products are medical devices intended for professional use only and must be administered by trained healthcare professionals in accordance with the approved instructions for use in each market.
Teoxane was the first company to obtain MDR certification for its full TEOSYAL® PureSense and TEOSYAL RHA® ranges, reinforcing its standards for efficacy, quality, and safety in Hyaluronic Acid-based wrinkle treatments. The company also states that this certification is supported by clinical data and by rigorous assessment requirements under European regulations.
In addition, RHA® 2, RHA® 3, and RHA® 4 have been FDA approved since 2017 for indications related to moderate to severe dynamic wrinkles. This milestone further confirms Teoxane’s scientific foundation and clinical credibility in the field of fillers and injectable skin rejuvenation.