TargetCool® is a precise, controlled CO₂ cooling device designed for use in medical and aesthetic treatments, helping elevate the treatment experience by making procedures gentler, safer, and more comfortable. With its ability to rapidly cool the treatment area, the device helps reduce pain, swelling, inflammation, and bruising during and after procedures, while also supporting a smoother recovery process.
Device Role
TargetCool® helps optimize treatment workflows through precise temperature control, flexible timing adjustment, and easy operation. It allows practitioners to cool the target area according to the desired settings, thereby enhancing clinical precision and improving the overall treatment experience.
Applied Technology
TargetCool® utilizes controlled cryotherapy, combining 99.9% pure CO₂ with a digital modulation system, infrared sensor, and calibrated nozzle to deliver rapid, precise, and stable cooling to the skin surface. Accurate control of temperature and cooling time helps reduce the risk of tissue damage while improving reproducibility and clinical performance.
Three Modes in One Device
TargetCool® integrates three treatment modes with different temperature ranges to support a variety of applications:
- Cooling Mode (-10°C to 5°C): helps reduce pain, discomfort, inflammation, and swelling
- Boosting Mode (2°C to 4°C): helps enhance the absorption of active ingredients into the dermis while reducing pain and discomfort
- Freezing Mode (-79°C): supports cryosurgery and the treatment of certain skin lesions
Clinical Applications
TargetCool® can be used in a wide range of treatments, including fillers, toxin injections, PRP, mesotherapy, skin boosters, PDO thread lifting, RF microneedling, MTS, fractional laser, pigmentation treatments, and tattoo removal. The device is particularly well suited for procedures where improved patient comfort and faster post-treatment recovery are desired.
Key Benefits
For practitioners: supports precise targeting, improves handling, and helps optimize treatment efficiency.
For patients: helps reduce pain and discomfort, eliminates the waiting time associated with topical anesthetics, and supports a more comfortable recovery after treatment.
At the core of TargetCool is the combination of advanced cryogenics and digital control, allowing precise management of temperature and exposure time according to each treatment objective. The system uses 99.9% pure CO₂ in a 100% aluminum cartridge, helping ensure purity of the cooling gas while optimizing stability and durability in clinical use.
The TargetCool platform is built around three main modes:
- Cooling: rapid skin cooling to support pain reduction and, in some cases, reduce or replace the need for topical anesthesia in sensitive procedures
- Boosting: delivery of cryo-frozen particles to support the transdermal penetration of active ingredients such as exosomes, hyaluronic acid, PDRN, and EGF without injection
- Freezing: controlled cryosurgery for epidermal lesions such as warts, seborrheic keratoses, and skin tags
A key advantage of TargetCool is its ability to combine pain management, soothing, transdermal delivery support, and targeted treatment within one technology platform. In addition to clinical utility, the device is strongly positioned around patient comfort, ease of handling, and procedural flexibility across multiple treatment settings.
TargetCool is suitable for indications that require precise cooling before, during, or after a procedure. In Cooling mode, the device is commonly used before treatments such as filler, botulinum toxin, PRP, Sculptra, and mesotherapy, and is particularly useful for sensitive areas including the perioral region, periocular area, scalp, or treatment zones for hyperhidrosis. In inflammatory conditions, Cooling mode may also support soothing and reduction of inflammatory acne lesions.
In Boosting mode, TargetCool is well suited for post-treatment care after RF microneedling, fractional laser, and other energy-based procedures, while also serving as a non-invasive support solution for transdermal delivery of active ingredients in patients with sensitive skin or low tolerance to injectable skin boosters. In Freezing mode, the device is appropriate for selective cryotherapy of certain benign epidermal lesions.
In terms of operation, the system is designed to be intuitive: the practitioner selects the temperature, exposure time, or treatment mode, positions the handpiece at the appropriate angle, and activates the spray. Modes such as Continuous, PL, and Manual allow flexible adjustment according to the indication and treatment area.
TargetCool is developed on a precision cooling technology platform that meets FDA, CE, and MFDS standards, while the company also operates under ISO 13485 and GMP quality systems for medical device manufacturing. This provides an important foundation for the device’s safety, reliability, and international clinical applicability.
In addition, TargetCool is supported by a growing body of publications and clinical data related to pain reduction during procedures, transdermal delivery support, acne management, scalp applications, and precision cryotherapy. The combination of standardized technology, multi-indication versatility, and clinical evidence positions TargetCool as a high-value precision cooling solution in dermatology and aesthetic medicine.
To go further with Target Cool
More than a conventional cooling solution, TargetCool is designed as a multi-mode precision cooling platform, combining Cooling, Boosting, and Freezing in one device. This approach expands its use from support in filler, botulinum toxin, PRP, Sculptra, and mesotherapy procedures to post-treatment care after RF microneedling, fractional laser, energy-based device treatments, and selective management of epidermal lesions.