{"id":571,"date":"2026-04-08T11:32:26","date_gmt":"2026-04-08T11:32:26","guid":{"rendered":"https:\/\/grassroots.com.vn\/?p=571"},"modified":"2026-07-06T13:18:27","modified_gmt":"2026-07-06T08:18:27","slug":"the-application-of-aesthefill-pdlla-cmc-in-skin-rejuvenation","status":"publish","type":"post","link":"https:\/\/grassroots.com.vn\/en\/the-application-of-aesthefill-pdlla-cmc-in-skin-rejuvenation\/","title":{"rendered":"The Application of AestheFill PDLLA-CMC in Skin Rejuvenation"},"content":{"rendered":"<p><span data-contrast=\"auto\">In recent years, skin rejuvenation has evolved beyond the traditional focus on volume restoration or surface-level correction. Instead, modern treatment approaches are placing greater emphasis on skin quality, overall facial harmony, and safety in clinical practice. This shift is also why solutions that support collagen stimulation and dermal restructuring from within are receiving increasing attention from aesthetic professionals.<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">This treatment philosophy was clearly reflected in the scientific workshop titled\u00a0<\/span><b><span data-contrast=\"auto\">\u201cThe Application of PDLLA-CMC in Skin Rejuvenation: From Collagen-Stimulating Efficacy to Clinical Safety,\u201d<\/span><\/b><span data-contrast=\"auto\">\u00a0co-organized by the University Medical Center Ho Chi Minh City and Grassroots on\u00a0<\/span><b><span data-contrast=\"auto\">March 15, 2026<\/span><\/b><span data-contrast=\"auto\">. The program offered a multidimensional perspective on AestheFill PDLLA-CMC, covering its mechanism of action, clinical response, and important safety considerations in real-world treatment settings.<\/span><\/p>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_855\" aria-describedby=\"caption-attachment-855\" style=\"width: 2155px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-855 \" src=\"https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014606_9e0efd201413e437cf6b8cef7f6bce99.jpg\" alt=\"Asthefill\" width=\"2155\" height=\"1436\" srcset=\"https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014606_9e0efd201413e437cf6b8cef7f6bce99.jpg 2048w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014606_9e0efd201413e437cf6b8cef7f6bce99-300x200.jpg 300w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014606_9e0efd201413e437cf6b8cef7f6bce99-1024x683.jpg 1024w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014606_9e0efd201413e437cf6b8cef7f6bce99-768x512.jpg 768w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014606_9e0efd201413e437cf6b8cef7f6bce99-1536x1024.jpg 1536w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014606_9e0efd201413e437cf6b8cef7f6bce99-350x233.jpg 350w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014606_9e0efd201413e437cf6b8cef7f6bce99-600x400.jpg 600w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014606_9e0efd201413e437cf6b8cef7f6bce99-uai-720x480.jpg 720w\" sizes=\"(max-width: 2155px) 100vw, 2155px\" \/><figcaption id=\"caption-attachment-855\" class=\"wp-caption-text\">Overview of the scientific workshop on the application of PDLLA-CMC in skin rejuvenation.<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center;\" aria-level=\"2\">AestheFill PDLLA-CMC and Today\u2019s Rejuvenation Trends<\/h2>\n<p>&nbsp;<\/p>\n<p><span data-contrast=\"auto\">As aesthetic expectations continue to change, treatment goals are changing as well. While immediate visible results were once the primary focus, skin rejuvenation today is increasingly moving toward outcomes that look more natural, feel softer, and place greater value on tissue quality.<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Within this context, AestheFill PDLLA-CMC is being discussed as part of a regenerative approach to skin rejuvenation, rather than simply as a product associated with superficial change. This reflects a direction that is becoming more relevant in modern aesthetic dermatology, where long-term skin quality and structural support are gaining greater clinical importance.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center;\" aria-level=\"2\">A Scientific Workshop Featuring Leading Experts in Aesthetic Dermatology<\/h2>\n<p>&nbsp;<\/p>\n<p><span data-contrast=\"auto\">The workshop was chaired by\u00a0<\/span><b><span data-contrast=\"auto\">Assoc. Prof. Dr. Le Thai Van Thanh<\/span><\/b><span data-contrast=\"auto\">, Head of the Department of Dermatology and Skin Aesthetics at the University Medical Center Ho Chi Minh City, and Senior Lecturer in Dermatology at the University of Medicine and Pharmacy at Ho Chi Minh City.<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The speaker panel included\u00a0<\/span><b><span data-contrast=\"auto\">Dr. Camelo Crisafulli (Italy), MSc. Dr. Pham Cam Thuy, MSc. Dr. Ta Quoc Hung,<\/span><\/b><span data-contrast=\"auto\">\u00a0and\u00a0<\/span><b><span data-contrast=\"auto\">Specialist Level II Dr. Thach Van Toan<\/span><\/b><span data-contrast=\"auto\">. The participation of both Vietnamese and international experts brought academic depth to the program while also making the discussions highly relevant to daily clinical practice in Vietnam.<\/span><\/p>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_856\" aria-describedby=\"caption-attachment-856\" style=\"width: 2560px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"size-full wp-image-856\" src=\"https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014510_26e60a52e1f5af747c926804b8561278.jpg\" alt=\"Aesthefill\" width=\"2560\" height=\"1582\" srcset=\"https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014510_26e60a52e1f5af747c926804b8561278.jpg 2560w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014510_26e60a52e1f5af747c926804b8561278-300x185.jpg 300w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014510_26e60a52e1f5af747c926804b8561278-1024x633.jpg 1024w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014510_26e60a52e1f5af747c926804b8561278-768x475.jpg 768w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014510_26e60a52e1f5af747c926804b8561278-1536x949.jpg 1536w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014510_26e60a52e1f5af747c926804b8561278-2048x1266.jpg 2048w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014510_26e60a52e1f5af747c926804b8561278-350x216.jpg 350w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014510_26e60a52e1f5af747c926804b8561278-600x371.jpg 600w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/><figcaption id=\"caption-attachment-856\" class=\"wp-caption-text\">Representatives of the organizing committee presenting certificates of appreciation to the speakers.<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_854\" aria-describedby=\"caption-attachment-854\" style=\"width: 2560px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"size-full wp-image-854\" src=\"https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014608_ab5de2d0f3f355bc209786d6d74034ba.jpg\" alt=\"Aesthefill\" width=\"2560\" height=\"1627\" srcset=\"https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014608_ab5de2d0f3f355bc209786d6d74034ba.jpg 2560w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014608_ab5de2d0f3f355bc209786d6d74034ba-300x191.jpg 300w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014608_ab5de2d0f3f355bc209786d6d74034ba-1024x651.jpg 1024w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014608_ab5de2d0f3f355bc209786d6d74034ba-768x488.jpg 768w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014608_ab5de2d0f3f355bc209786d6d74034ba-1536x976.jpg 1536w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014608_ab5de2d0f3f355bc209786d6d74034ba-2048x1302.jpg 2048w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014608_ab5de2d0f3f355bc209786d6d74034ba-350x222.jpg 350w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014608_ab5de2d0f3f355bc209786d6d74034ba-600x381.jpg 600w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/><figcaption id=\"caption-attachment-854\" class=\"wp-caption-text\">Representatives of the organizing committee and speakers at the workshop on the application of PDLLA-CMC in skin rejuvenation.<\/figcaption><\/figure>\n<h2 style=\"text-align: center;\" aria-level=\"2\">AestheFill PDLLA-CMC in Regenerative Skin Rejuvenation<\/h2>\n<p>&nbsp;<\/p>\n<p><span data-contrast=\"auto\">At the workshop,\u00a0<\/span><b><span data-contrast=\"auto\">Dr. Camelo Crisafulli<\/span><\/b><span data-contrast=\"auto\">\u00a0shared insights into the use of PDLLA-CMC in improving visible signs of aging. His presentation highlighted a regenerative approach to skin rejuvenation, where treatment goals are no longer limited to immediate visual correction, but instead aim for natural-looking enhancement, facial harmony, and progressive improvement over time.<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">In this context, AestheFill was presented as a solution associated with collagen stimulation and dermal restructuring, aligning with the direction of modern rejuvenation strategies. Its presence in scientific discussions also reflects the growing clinical interest in approaches that go beyond surface correction and instead focus on improving tissue quality from within.<\/span><\/p>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_857\" aria-describedby=\"caption-attachment-857\" style=\"width: 2560px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"size-full wp-image-857\" src=\"https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014445_5af71c1230a1940f272475e295658ac0.jpg\" alt=\"Aesthefill\" width=\"2560\" height=\"1793\" srcset=\"https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014445_5af71c1230a1940f272475e295658ac0.jpg 2560w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014445_5af71c1230a1940f272475e295658ac0-300x210.jpg 300w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014445_5af71c1230a1940f272475e295658ac0-1024x717.jpg 1024w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014445_5af71c1230a1940f272475e295658ac0-768x538.jpg 768w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014445_5af71c1230a1940f272475e295658ac0-1536x1076.jpg 1536w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014445_5af71c1230a1940f272475e295658ac0-2048x1434.jpg 2048w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014445_5af71c1230a1940f272475e295658ac0-350x245.jpg 350w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626714014445_5af71c1230a1940f272475e295658ac0-600x420.jpg 600w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/><figcaption id=\"caption-attachment-857\" class=\"wp-caption-text\">The scientific presentations focused on the application of PDLLA-CMC in improving signs of aging.<\/figcaption><\/figure>\n<h2 style=\"text-align: center;\" aria-level=\"2\">Clinical Response and Safety in PDLLA-CMC Applications<\/h2>\n<p>&nbsp;<\/p>\n<p><span data-contrast=\"auto\">From a practical perspective, the workshop extended beyond mechanism of action to address clinical response and safety in actual use.<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"auto\">MSc. Dr. Pham Cam Thuy<\/span><\/b><span data-contrast=\"auto\">\u00a0presented an evaluation of clinical response following PDLLA-CMC treatment in Vietnam. Her presentation contributed valuable real-world insight, helping attendees better understand the clinical relevance and potential role of this approach in the local setting.<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">In addition,\u00a0<\/span><b><span data-contrast=\"auto\">MSc. Dr. Ta Quoc Hung<\/span><\/b><span data-contrast=\"auto\">\u00a0shared safety strategies and complication management approaches related to the use of PDLLA-CMC. This part of the program reinforced an important principle in aesthetic medicine: efficacy cannot be separated from safety. In clinical practice, outcomes depend not only on the product itself, but also on physician experience, careful patient selection, and an appropriate treatment strategy for each individual case.<\/span><\/p>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_853\" aria-describedby=\"caption-attachment-853\" style=\"width: 2048px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"size-full wp-image-853\" src=\"https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626717187014_0b70ffeb99e743beffef73aa7f1929d5.jpg\" alt=\"Aesthefill\" width=\"2048\" height=\"1365\" srcset=\"https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626717187014_0b70ffeb99e743beffef73aa7f1929d5.jpg 2048w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626717187014_0b70ffeb99e743beffef73aa7f1929d5-300x200.jpg 300w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626717187014_0b70ffeb99e743beffef73aa7f1929d5-1024x683.jpg 1024w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626717187014_0b70ffeb99e743beffef73aa7f1929d5-768x512.jpg 768w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626717187014_0b70ffeb99e743beffef73aa7f1929d5-1536x1024.jpg 1536w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626717187014_0b70ffeb99e743beffef73aa7f1929d5-350x233.jpg 350w, https:\/\/grassroots.com.vn\/wp-content\/uploads\/2026\/04\/z7626717187014_0b70ffeb99e743beffef73aa7f1929d5-600x400.jpg 600w\" sizes=\"(max-width: 2048px) 100vw, 2048px\" \/><figcaption id=\"caption-attachment-853\" class=\"wp-caption-text\">The workshop emphasized both clinical efficacy and safety in the application of PDLLA-CMC.<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center;\" aria-level=\"2\">Live Demonstration Bridging Theory and Practice<\/h2>\n<p>&nbsp;<\/p>\n<p><span data-contrast=\"auto\">Alongside the academic presentations, the workshop also featured a live demonstration of PDLLA-CMC applications for rejuvenation of the face, neck, and hands, performed by\u00a0<\/span><b><span data-contrast=\"auto\">Specialist Level II Dr. Thach Van Toan<\/span><\/b><span data-contrast=\"auto\">. This session helped attendees better visualize how the approach can be applied in real treatment settings, while also strengthening the connection between scientific knowledge and hands-on clinical practice.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: center;\" aria-level=\"2\">What Is AestheFill?<\/h2>\n<h2 style=\"text-align: center;\" aria-level=\"2\"><span data-ccp-props=\"{&quot;134245418&quot;:false,&quot;134245529&quot;:false,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:360,&quot;335559739&quot;:80}\">\u00a0<\/span><\/h2>\n<p><span data-contrast=\"auto\">AestheFill is a product composed of microparticles containing\u00a0<\/span><b><span data-contrast=\"auto\">PDLLA (Poly-D,L-Lactic Acid)<\/span><\/b><span data-contrast=\"auto\">\u00a0combined with\u00a0<\/span><b><span data-contrast=\"auto\">CMC (Carboxymethylcellulose)<\/span><\/b><span data-contrast=\"auto\">. It supports the body\u2019s natural collagen stimulation process, contributing to dermal regeneration from within and promoting longer-term rejuvenation outcomes.<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The introduction of AestheFill PDLLA-CMC within the framework of this scientific workshop also shows that the product is being positioned within a broader trend in skin rejuvenation\u2014one that increasingly values mechanism-driven treatment, appropriate clinical indication, and closer patient monitoring.<\/span><\/p>\n<hr \/>\n<blockquote><p><b><span data-contrast=\"auto\">AestheFill \u2013 A Natural, Science-Driven, and Sustainable Rejuvenation Solution<\/span><\/b><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:60,&quot;335559739&quot;:60,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.facebook.com\/aesthefillvn\" target=\"_blank\" rel=\"noopener\">Explore more about LDLLA-CMC technology and the science of collagen-based rejuvenation<\/a><\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>In recent years, skin rejuvenation has evolved beyond the traditional focus on volume restoration or surface-level correction. Instead, modern treatment [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":855,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-571","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.9) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>The Application of AestheFill PDLLA-CMC in Skin Rejuvenation | Grassroots<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/grassroots.com.vn\/en\/the-application-of-aesthefill-pdlla-cmc-in-skin-rejuvenation\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Application of AestheFill PDLLA-CMC in Skin Rejuvenation\" \/>\n<meta property=\"og:description\" content=\"In recent years, skin rejuvenation has evolved beyond the traditional focus on volume restoration or surface-level correction. 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